Annie Wilkes
Fans of Thrillers know that Stephen King is the author to read if you do not mind ever sleeping again. One of his most iconic film adaptations is Misery, which has one of the evilest nurses of all time as its main character.
Annie Wilkes is a maternity nurse who comes across her favorite author and does not plan on letting him go. Kathy Bates brought her to life, and, of course, her fantastic performance won her an Oscar.